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Figure 4: | Standards in Genomic Sciences

Figure 4:

From: Quantifying Protein Function Specificity in the Gene Ontology

Figure 4:

Correlation between different measurements of function specificity. This scatter-plot matrix of each pair of specificity measures shows the ways in which they are correlated with each other. Each individual row and column contains comparisons for the particular variables with the rows corresponding to the y-axis and columns to the x-axis. For instance, for the IC and Offsp plot in the lower quadrant, the y-axis is Offsp (0-8) and the x-axis is IC (0-15). In the upper quadrant this is reversed. The variables in the pairs plot are the aforementioned IC and Offsp (normalized); as well as NumAnc (the number of GO ancestors of a term); and GOprop (the proportion considering both number of ancestors and number of offspring of a term). As is shown in this graph, there is strong correlation between each of the variables but not exactly, indicating each one has information about specificity another might not have.

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